Quantification of resting myocardial blood flow velocity in normal humans using real-time contrast echocardiography. A feasibility study.

ABSTRACT:

Background

Real-time myocardial contrast echocardiography (MCE) is a novel method for assessing myocardial perfusion. The aim of this study was to evaluate the feasibility of a very low-power real-time MCE for quantification of regional resting myocardial blood flow (MBF) velocity in normal human myocardium.

Methods

Twenty study subjects with normal left ventricular (LV) wall motion and normal coronary arteries, underwent low-power real-time MCE based on color-coded pulse inversion Doppler. Standard apical LV views were acquired during constant IV. infusion of SonoVue. Following transient microbubble destruction, the contrast replenishment rate (beta), reflecting MBF velocity, was derived by plotting signal intensity vs. time and fitting data to the exponential function; y (

SUBMITTER: Malm S 

PROVIDER: S-EPMC1184091 | biostudies-literature | 2005 Jun

REPOSITORIES: biostudies-literature