Association between physical activity and diabetes mellitus: mediation analysis involving Systemic Immune-Inflammatory Index in a cross-sectional NHANES study.

ABSTRACT:

Objectives

In this study, we aimed to clarify the relationship between physical activity (PA) and diabetes mellitus (DM), as well as the mediating role of Systemic Immune-Inflammatory Index (SII) in the relationship.

Design

A cross-sectional study.

Setting

National Health and Nutrition Examination Survey (NHANES) data collection took place in the USA at participants' homes and mobile examination centres with specialised equipment.

Participants

The study population consisted of 9493 American adults aged 20 and above from the NHANES 2005 to 2018.

Primary and secondary outcome measures

Information on the specific PA was reported through self-administered questionnaire by participants and we used this information to calculate a metabolic equivalent score for

SUBMITTER: Chen Y 

PROVIDER: S-EPMC11840911 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature