A Chinese drug-compatibility-based approach to purslane hydrogels for acute eczema therapy.

ABSTRACT: Purslane (Portulaca oleracea L.) with heat-clearing and detoxicating, anti-inflammatory and resolving swelling, relieving itching and astringing function, has remarkable efficacy for acute eczema. However, most of the clinical applications of purslane are freshly prepared decoction, not as easy to apply as cream, because the decoction is easy to breed bacteria and easy to oxidize. Here, based on the theory of Chinese medicines compatibility, we made a purslane-tannic acid hydrogel (PL-HATA) by simple methods under mild conditions to solve the drawbacks of easy oxidation and inconvenience of use of Purslane. The antimicrobial activity of PL-HATA hydrogel can exert an excellent antimicrobial effect, reducing the flora on the skin of acute eczema and further relieving the symptoms of a

SUBMITTER: Wang L 

PROVIDER: S-EPMC11841398 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature