A case series of patients with cardiac amyloidosis evaluated at a Colombian university hospital.

ABSTRACT:

Background

In Colombia, the characteristics of cardiac amyloidosis (CA)-including wild-type transthyretin amyloidosis (ATTRwt), immunoglobulin light chain amyloidosis (AL), and genetic variant transthyretin amyloidosis (ATTRv)-are underexplored.

Methods

This case series at a Colombian university hospital analyzed demographic, clinical, laboratory, radiological, and genetic data of CA patients diagnosed between 2018 and 2022. Patients with incomplete data underwent further testing.

Results

Of 24 identified patients, 14 were included after exclusions. The majority were male (73.3%), with an average age of 70.6 years. ATTRv and AL were equally prevalent (42.8%), followed by ATTRwt (14.2%). The p.Val142Ile TTR mutation was found among all ATTRv patients. Most presented wi

SUBMITTER: Lopez-Ponce de Leon JD 

PROVIDER: S-EPMC11841452 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature