A national population-based study of mortality and risk factors in COVID-19-hospitalized patients in Spain (2020-2021).

ABSTRACT:

Objectives

The study aimed to analyze in-hospital mortality (IHM) among all COVID-19 patients hospitalized in Spain between March 1, 2020, and December 31, 2021, and to compare two distinct periods: the prevaccination period (March 1, 2020, to January 31, 2021) and the vaccination period (February 1, 2021, to December 31, 2021). The objective was to assess the impact of vaccination on IHM and identify associated risk factors, using data from Spain's national hospitalization registry.

Methods

This retrospective analysis used data from the Spanish National Surveillance System for Hospital Data. The primary outcome was in-hospital mortality (IHM). Multivariate logistic regression identified risk factors across the overall study period, as well as during the prevaccination and v

SUBMITTER: Ramos-Rincon JM 

PROVIDER: S-EPMC11841506 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature