The effect of perioperative probiotics and synbiotics on postoperative infections in patients undergoing major liver surgery: a meta-analysis of randomized controlled trials.

ABSTRACT:

Objective

To evaluate the effect of perioperative probiotics or synbiotics on the incidence of postoperative infections following major liver surgery.

Design

Meta-analysis.

Data sources

PubMed, Embase, Scopus, and the Cochrane Library for relevant English-language studies published up to February 21st, 2024.

Eligibility criteria

Randomized controlled trials evaluating perioperative probiotics or synbiotics for preventing postoperative infections in patients undergoing major liver surgery.

Data extraction and synthesis

Outcomes included postoperative infection incidence, antibiotic therapy duration, length of stay in intensive care unit (ICU) and hospital. A random-effect model was adopted for the meta-analysis. The quality of included studies was evaluat

SUBMITTER: Wu H 

PROVIDER: S-EPMC11841616 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature