Cross-sectional association between plasma aldosterone concentration and cognitive performance by mini-mental state examination in community dwellers.

ABSTRACT:

Background

Aldosterone is the effector hormone in the renin angiotensin aldosterone system and existing data suggest aldosterone affect cognitive function. However, the relationship between plasma aldosterone concentration (PAC) and cognitive performance remains unexplored in community dwellers. Therefore, we aimed to explore whether PAC is associated with cognitive performance in this population.

Methods

We cross-sectionally enrolled adults using multistage random sampling from Emin, China in 2019. Participants underwent questionnaires and data collection. Cognitive status was assessed using mini-mental state examination (MMSE) questionnaire. Multi-variable linear and logistic regression were used to explore the association between log PAC and log MMSE score, and between te

SUBMITTER: Nusufujiang A 

PROVIDER: S-EPMC11841653 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature