Nanoporous platinum microelectrode arrays for neuroscience applications.

ABSTRACT: Microelectrode arrays are invaluable tools for investigating the electrophysiological behaviour of neuronal networks with high spatiotemporal precision. In recent years, it has become increasingly common to functionalize such electrodes with highly porous platinum to increase their effective surface area, and hence their signal-to-noise ratio. Although such functionalization significantly improves the electrochemical performance of the electrodes, the impact of various electrode morphologies on biocompatibility and electrophysiological performance in cell cultures remains poorly understood. In this study, we introduce reproducible protocols for depositing highly porous platinum with varying morphologies on microelectrodes designed for neural cell cultures. We also evaluate the impact of mo

SUBMITTER: Winter-Hjelm N 

PROVIDER: S-EPMC11841673 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature