Advancing malaria reactive case detection in a Zambia-like setting: A modeling study.

ABSTRACT: In Zambia-like settings, asymptomatic and clinical carriers not seeking treatment further complicate malaria elimination, making reactive case detection (RCD) essential for identifying undetected infections. However, RCD faces operational hurdles, including resource shortages, logistical challenges, limited community health workers (CHWs), and limitations in availability and sensitive rapid diagnostic tests (RDTs). Prioritizing specific improvement measures is critical to enhance intervention outcomes. A mathematical model of malaria transmission for low-transmission areas (fewer than 200 cases per 1,000 annually) was developed using published data to simulate RCD. This model assessed the impact of potential improvement measures designed to address the identified operational challenges aff

SUBMITTER: Chiziba C 

PROVIDER: S-EPMC11841873 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature