Mettannotator: a comprehensive and scalable Nextflow annotation pipeline for prokaryotic assemblies.

ABSTRACT:

Summary

In recent years, there has been a surge in prokaryotic genome assemblies, coming from both isolated organisms and environmental samples. These assemblies often include novel species that are poorly represented in reference databases creating a need for a tool that can annotate both well-described and novel taxa, and can run at scale. Here, we present mettannotator-a comprehensive, scalable Nextflow pipeline for prokaryotic genome annotation that identifies coding and noncoding regions, predicts protein functions, including antimicrobial resistance, and delineates gene clusters. The pipeline summarizes these results in a GFF (General Feature Format) file that can be easily utilized in downstream analysis or visualized using common genome browsers. Here, we show how it works

SUBMITTER: Gurbich TA 

PROVIDER: S-EPMC11842068 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature