Computational fluid dynamics to simulate stenotic lesions in coronary end-to-side anastomosis.

ABSTRACT:

Objectives

End-to-side anastomosis is common in coronary artery bypass grafting, although restrictive suturing can narrow the anastomosis. We evaluated ex vivo end-to-side models by numerically simulating fluid dynamics to compare various degrees of stenotic anastomoses to predict haemodynamic effects.

Methods

A carotid artery was grafted via an end-to-side anastomosis onto the left anterior descending artery of a porcine heart, with liquid silicone injected into the vessels. The end-to-side image was acquired via multidetector computed tomography for reference, and models of longitudinal shortening and bilateral narrowing were created with 25%, 50%, 75%, along with 90%, and 100% stenosis in the native coronary artery. Haemodynamics were analysed using computational fluid dy

SUBMITTER: Kamiya K 

PROVIDER: S-EPMC11842071 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature