Impact of Race and Ethnicity on Outcomes After Umbilical Cord Blood Transplantation.

ABSTRACT:

Background

Umbilical cord blood transplant (UCBT) improves access to transplant for patients lacking a fully matched donor. Previous Center for International Blood and Marrow Transplant Research (CIBMTR) showed that Black patients had a lower overall survival (OS) than White patients following single UCBT. The current study draws on a larger modern cohort and compares outcomes among White, Latinx, Black, and Asian patients.

Objective

To compare outcomes by social determinants of health.

Study design

We designed a retrospective study using CIBMTR data. US patients were between ages 1 and 80; 983 received single and 1529 double UCBT as reported to CIBMTR, following either a myeloablative (N = 1752) or reduced intensity conditioning (N = 759) for acute myeloid leukemia,

SUBMITTER: Ballen K 

PROVIDER: S-EPMC11842128 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature