Phosphorylated glycosphingolipids are commonly detected in Caenorhabditis elegans lipidomes.

ABSTRACT:

Introduction

The identification of lipids is a cornerstone of lipidomics, and due to the specific characteristics of lipids, it requires dedicated analysis workflows. Identifying novel lipids and lipid species for which no reference spectra are available is tedious and often involves a lot of manual work. Integrating high-resolution mass spectrometry with enhancements from chromatographic and ion mobility separation enables the in-depth investigation of intact lipids.

Objectives

We investigated phosphorylated glycosphingolipids from the nematode Caenorhabditis elegans, a biomedical model organism, and aimed to identify different species from this class of lipids, which have been described in one particular publication only. We checked if these lipids can be detected in lipid

SUBMITTER: Witting M 

PROVIDER: S-EPMC11842410 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature