Fluorescence confocal microscopy for margin assessment in prostatectomy: IP8-FLUORESCE study protocol.

ABSTRACT:

Background

Radical prostatectomy (RP) represents the cornerstone of surgical treatment for prostate cancer. Assessing surgical margin status intraoperatively with current techniques remains challenging due to high costs in the context of an already stretched pathology workforce. Fluorescence confocal microscopy (FCM) is a promising technique to detect margins in prostate cancer surgery not bound by such limitations.

Study design

The Imperial Prostate 8 - Fluorescence Confocal Microscopy for Rapid Evaluation of Surgical Cancer Excision (IP8-FLUORESCE) study is a multicentre, prospective, ex vivo, 'blinded', comparative cohort study. It aims to assess the accuracy of digital FCM for detection of prostate cancer at surgical margins compared to traditional histopathology.

End

SUBMITTER: Mayor N 

PROVIDER: S-EPMC11842882 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature