Performance evaluation of colistin rapid NP test for detection of colistin resistance in colistin resistant <i>Enterobacterales</i>.

ABSTRACT:

Background

Carbapenem-resistant Enterobacterales (CRE) have become a global threat, with colistin being the last resort for treatment. CLSI and EUCAST recommend broth microdilution (BMD) as the reference method for colistin susceptibility testing. Nordmann and Poirel have developed a simple and rapid Polymyxin NP test as an alternative to BMD for screening of colistin-resistant Enterobacterale (CoRE) isolates. This study aimed to evaluate the performance of the colistin rapid NP (CRNP) test for the detection of colistin resistance.

Methods

CRNP test was performed on thirty-one clinical Enterobacterales isolates [Klebsiella pneumoniae (21), Enterobacter spp, (9) and Escherichia coli (1), which were resistant to Colistin by the referen

SUBMITTER: Kar P 

PROVIDER: S-EPMC11842924 | biostudies-literature | 2024 Nov-Dec

REPOSITORIES: biostudies-literature