Risk prediction of cardiovascular disease in the Asia-Pacific region: the SCORE2 Asia-Pacific model.

ABSTRACT:

Background and aims

To improve upon the estimation of 10-year cardiovascular disease (CVD) event risk for individuals without prior CVD or diabetes mellitus in the Asia-Pacific region by systematic recalibration of the SCORE2 risk algorithm.

Methods

The sex-specific and competing risk-adjusted SCORE2 algorithms were systematically recalibrated to reflect CVD incidence observed in four Asia-Pacific risk regions, defined according to country-level World Health Organization age- and sex-standardized CVD mortality rates. Using the same approach as applied for the original SCORE2 models, recalibration to each risk region was completed using expected CVD incidence and risk factor distributions from each region.

Results

Risk region-specific CVD incidence was estimated using

SUBMITTER: SCORE2 Asia-Pacific writing group 

PROVIDER: S-EPMC11842970 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature