Temperature Excursion of Intravitreal Anti-VEGF Agents During Home Storage.

ABSTRACT:

Importance

Some patients worldwide are asked to acquire an anti-vascular endothelial growth factor (anti-VEGF) agent from a pharmacy, store it, and then bring it to a physician for intravitreal injection (IVT). Anti-VEGF agents must be stored in the refrigerator to avoid bacterial contamination or denaturation. Some cases of severe intraocular inflammation have been reported following IVT of more recently approved anti-VEGF agents, which might be explained by thermal instability.

Objective

To investigate whether patients followed the storage temperature guidelines for intravitreal anti-VEGF agents in daily clinical practice.

Design, setting, and participants

This quality improvement study, performed between May 27 and June 7, 2024, at the Ophthalmology Department of D

SUBMITTER: Ben Ghezala I 

PROVIDER: S-EPMC11843350 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature