Cancer Risk and Estimated Lithium Exposure in Drinking Groundwater in the US.

ABSTRACT:

Importance

Lithium is a naturally occurring element in drinking water and is commonly used as a mood-stabilizing medication. Although clinical studies have reported associations between receiving lithium treatment and reduced cancer risk among patients with bipolar disorder, to our knowledge, the association between environmental lithium exposure and cancer risk has never been studied in the general population.

Objectives

To evaluate the association between exposure to lithium in drinking groundwater and cancer risk in the general population.

Design, setting, and participants

This cohort study included participants with electronic health record and residential address information but without cancer history at baseline from the All of Us Research Program between May 31

SUBMITTER: Luo J 

PROVIDER: S-EPMC11843356 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature