Oncological Safety of MRI-Informed Biopsy Decision-Making in Men With Suspected Prostate Cancer.

ABSTRACT:

Importance

The magnetic resonance imaging (MRI) pathway for diagnosing clinically significant prostate cancer (csPCa; defined as International Society of Urological Pathology grade group ≥2) uses multiparametric MRI (mpMRI) for prostate biopsy (PB) decision-making. However, the intermediate impact on patient outcomes in men with negative MRI results avoiding PB and men with positive MRI results without PCa remains unknown.

Objective

To assess the feasibility and safety of a community-based MRI diagnostic strategy in men with suspected PCa using 3-year active monitoring.

Design, setting, and participants

This multisite, longitudinal cohort trial took place across 54 community-based urology practices and 2 radiology imaging centers at a referral academic institution in

SUBMITTER: Hamm CA 

PROVIDER: S-EPMC11843366 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature