The triglyceride-glucose index and acute kidney injury risk in critically ill patients with coronary artery disease.

ABSTRACT:

Background

The triglyceride-glucose (TyG) index, proven a reliable and simple surrogate of insulin resistance, has shown potential associations with cardiovascular outcomes and renal diseases. This research delved into the utility of the TyG index in predicting the risk of acute kidney injury (AKI) in patients with coronary artery disease (CAD), an area not extensively covered in existing literature.

Methods

A cohort of patients with CAD was recruited from the Medical Information Mart for Intensive Care-IV database, and categorized into quartiles based on their TyG index. The primary outcome was AKI incidence, and the secondary outcome was renal replacement therapy (RRT). Scatterplot histograms, cox proportional hazards models, Kaplan-Meier survival curves, and restricted cu

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC11843639 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature