Beyond the infection: mapping the risk of cardiovascular events post-scrub typhus in a nationwide cohort study.

ABSTRACT: ABSTRACTScrub typhus, caused by Orientia tsutsugamushi, often involves multiple organs, but its cardiovascular (CV) sequelae in survivors remain under-researched. This retrospective cohort study analyzed data from the National Health Insurance Research Database (NHIRD) spanning 2010-2015 to assess CV risks among scrub typhus survivors. Excluding those with prior CV events, we focused on outcomes such as acute myocardial infarction (AMI), heart failure hospitalization (HFH), strokes, new-onset atrial fibrillation (AF), aortic aneurysm or dissection, venous thromboembolism (VTE), and CV death. From 2,269 scrub typhus patients without previous CV events (mean age 47.8 ± 16.1; 38.0% female), and a matched control group (n = 2,264), we observed a higher incidence of HFH, ne

SUBMITTER: Yeh JK 

PROVIDER: S-EPMC11843642 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature