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The relationship between serum uric acid level and non-alcoholic fatty liver disease in northern China: a retrospective cohort study.


ABSTRACT:

Background

Non-alcoholic fatty liver disease (NAFLD) has become the most prevalent chronic liver disease among adults. High uric acid (UA) increases the incidence of NAFLD in the general population. However, further exploration is warranted to determine the relationship between UA levels and NAFLD in various populations. We conducted a historical cohort study to investigate the causality between UA and NAFLD across different weight categories.

Methods

A historical cohort was established from the Jidong community cohort. All participants were enrolled and followed up from July 1st, 2013 to August 1st, 2018. The study participants were retrospectively assigned to four groups according to their UA levels (Q1, 69-210 μmol/L; Q2, 211-255 μmol/L; Q3, 256-310 

SUBMITTER: He Q 

PROVIDER: S-EPMC11843771 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature