Administration of dehydroepiandrosterone improves endometrial thickness in women undergoing IVF/ICSI: a systematic review and meta-analysis.

ABSTRACT:

Background

The positive effects of dehydroepiandrosterone (DHEA) on oocyte and embryo quality improvement are often concerned. While the results on DHEA-induced endometrial improvement are controversial.

Objective

To evaluate whether DHEA intervention improved endometrial function and reproductive outcomes during in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles and to thus provide clinical recommendations.

Data sources

PubMed, Cochrane Library, EMBASE and Web of Science from database inception to 31 July 2024, without language restrictions. The references of conference proceedings and websites on clinical trials were manually checked.

Study design

Systematic review and meta-analysis.

Study eligibility criteria

Parallel-controlled

SUBMITTER: Huang L 

PROVIDER: S-EPMC11843996 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature