Association between air pollution and cardiovascular disease risk in middle-aged and elderly individuals with diabetes: inflammatory lipid ratio accelerate this progression.

ABSTRACT:

Background

Long-term exposure to air pollution significantly increases the risk of cardiovascular disease (CVD); however, the association and underlying mechanisms in individuals with diabetes remain unconfirmed.

Methods

We used data from the China Health and Retirement Longitudinal Study (CHARLS) to follow 5,430 adults over a four-year period. Baseline CVD and diabetes status were determined, and high-resolution data were used to assess air pollution exposure to PM₁, PM_2.5, PM₁₀, and O₃. The inflammatory lipid ratio (ILR) was calculated to reflect inflammatory and lipid metabolic states. A generalized linear model (GLM) was employed to analyze the effects of air pollution and ILR on diabetes-related CVD risk.

Results

The pr

SUBMITTER: Yan C 

PROVIDER: S-EPMC11844067 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature