Core cooperative metabolism in low-complexity CO2-fixing anaerobic microbiota.

ABSTRACT: Biological conversion of carbon dioxide into methane has a crucial role in global carbon cycling and is operated by a specialised set of anaerobic archaea. Although it is known that this conversion is strictly linked with cooperative bacterial activity, such as through syntrophic acetate oxidation, there is also a limited understanding on how this cooperation is regulated and metabolically realised. In this work, we investigate the activity in a microbial community evolved to efficiently convert carbon dioxide into methane and predominantly populated by Methanothermobacter wolfeii. Through multi-omics, biochemical analysis and constraint-based modelling, we identify a potential formate cross-feeding from an uncharacterised Limnochordia species to M. wolfeii, driven by the recently discover

SUBMITTER: Zampieri G 

PROVIDER: S-EPMC11844248 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature