Changes of cell-type diversity in the polyp-to-medusa metagenesis of the scyphozoan jellyfish <i>Aurelia coerulea</i> (formerly sp.1).

ABSTRACT: The life cycle of most medusozoan cnidarians is marked by the metagenesis from the asexually reproducing sessile polyp and the sexually reproducing motile medusa. At present it is unknown to what extent this drastic morphological transformation is accompanied by changes in the cell type composition. Here, we provide a single cell transcriptome atlas of the cosmopolitan scyphozoan Aurelia coerulea focussing on changes in cell-type composition during the transition from polyp to medusa. Notably, this transition marked by an increase in cell type diversity, including an expansion of neural subtypes. We find that two families of neuronal lineages are specified by homologous transcription factors in the sea anemone Nematostella vectensis and Aurelia coerulea, suggesting an

SUBMITTER: Link O 

PROVIDER: S-EPMC11844373 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature