Development of the zebrafish anterior lateral line system is influenced by underlying cranial neural crest.

ABSTRACT: The mechanosensory lateral line system of aquatic vertebrates comprises a superficial network of distributed sensory organs, the neuromasts, which are arranged over the head and trunk and innervated by lateral line nerves to allow detection of changes in water flow and pressure. While the well-studied zebrafish posterior lateral line has emerged as a powerful model to study collective cell migration, far less is known about development of the anterior lateral line, which produces the supraorbital and infraorbital lines around the eye, as well as mandibular and opercular lines over the jaw and cheek. Here we show that normal development of the zebrafish anterior lateral line system from cranial placodes is dependent on another vertebrate-specific cell type, the cranial neural crest. We find

SUBMITTER: Venkataraman V 

PROVIDER: S-EPMC11844535 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature