Radiographic classification of mandibular osteoradionecrosis: A blinded prospective multi-disciplinary interobserver diagnostic performance study.

ABSTRACT:

Background

Osteoradionecrosis of the jaw (ORNJ) is a debilitating complication that affects up to 15% of head and neck cancer patients who undergo radiotherapy. The ASCO/ISOO/MASCC-endorsed ClinRad severity classification system was recently proposed (and recommended in the latest ASCO guidelines) to incorporate radiographic findings for determining ORNJ severity based on the vertical extent of bone necrosis. However, variability in imaging modalities and specialty-specific knowledge may contribute to disparities in diagnosing and classifying ORNJ. This study aims to evaluate and benchmark multi-specialty physician performance in diagnosing and severity classification of ORNJ using different radiographic imaging.

Methods

A single institution retrospective diagnostic validati

SUBMITTER: MD Anderson Head and Neck Cancer Symptom Working Group. 

PROVIDER: S-EPMC11844595 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature