The saNeuroGut Initiative: Investigating the Gut Microbiome and Symptoms of Anxiety, Depression, and Posttraumatic Stress.

ABSTRACT:

Introduction

Common mental disorders, such as anxiety disorders, depression, and posttraumatic stress disorder (PTSD), present a substantial health and economic burden. The gut microbiome has been associated with these psychiatric disorders via the microbiome-gut-brain axis. However, previous studies have focused on the associations between the gut microbiome and common mental disorders in European, North American, and Asian populations. As part of the saNeuroGut Initiative, we assessed associations between gut microbial composition and self-reported symptoms of anxiety, depression, and posttraumatic stress (PTS) among South African adults.

Methods

Participants completed validated, online self-report questionnaires to evaluate symptoms of state anxiety, trait anxiety, depres

SUBMITTER: O'Hare MA 

PROVIDER: S-EPMC11844704 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature