Cyclospora Genotypic Variations and Associated Epidemiologic Characteristics, United States, 2018-2021.

ABSTRACT: Seasonal cyclosporiasis outbreaks occur in the United States every year. To better understand the disease, the Centers for Disease Control and Prevention developed a novel genotyping system that successfully clusters nonclonal eukaryotes. We examined temporal-geographic distributions of Cyclospora cluster consensus genotypes (CCGs) and applied regression analyses to identify correlations between Cyclospora spp. parasites and clinical manifestations or epidemiologic risk factors, using data collected during 2018-2021. No CCG was uniquely associated with or consistently detected in a state during the study, suggesting that cyclosporiasis in the United States is likely caused by frequent parasite introductions. We identified positive associations between infection with C. ashfordi and C. caye

SUBMITTER: Shen J 

PROVIDER: S-EPMC11845137 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature