Identifying Different Immunoresistance Risk Profiles Among Experienced Aesthetic Botulinum Neurotoxin A Recipients: A Latent Class Analysis.

ABSTRACT:

Background

Immunoresistance to botulinum neurotoxin A (BoNT-A) due to neutralizing antibodies (NAbs) can lead to partial or complete secondary nonresponse (SNR), potentially limiting individuals' aesthetic and/or medical therapeutic options in the short and/or long term. Understanding factors directly or indirectly influencing BoNT-A immunoresistance risk is crucial.

Aims

This analysis explored patterns of latent risk factors (biological and behavioral) that may influence the risk of developing BoNT-A immunoresistance among experienced aesthetic BoNT-A recipients.

Methods

Latent class analysis (LCA) was applied to survey data from 363 experienced BoNT-A recipients from six Asia-Pacific countries to identify distinct subgroups based on their patterns of risk factor or

SUBMITTER: Tseng FW 

PROVIDER: S-EPMC11845912 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature