Short Duration of Antenatal Corticosteroid Exposure and Outcomes in Extremely Preterm Infants.

ABSTRACT:

Importance

When preterm delivery is imminent, it remains unclear whether the timing from administration of antenatal betamethasone to birth may reduce mortality and morbidity among extremely preterm infants.

Objective

To evaluate the association of duration from exposure to first dose of antenatal betamethasone with outcomes among extremely preterm infants.

Design, setting, and participants

This cohort study enrolled infants born at 22 0/7 to 27 6/7 weeks' gestation from January 2016 to February 2021 at National Institute of Child Health and Human Development Neonatal Research Network centers. Infants exposed to multiple doses of antenatal betamethasone, infants who did not receive intensive care, and infants with congenital anomalies were excluded. Data were analyzed

SUBMITTER: Chawla S 

PROVIDER: S-EPMC11846007 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature