Intrinsic functional brain connectivity in adolescent anxiety: Associations with behavioral phenotypes and cross-syndrome network features.

ABSTRACT:

Background

Considerable research has mapped the human brain networks implicated in anxiety. Yet, less is known about the intrinsic features of the brain implicated in adolescent anxiety and their generalizability to affective and behavioral problems. To this end, we investigated the intrinsic functional connectomes associated with anxiety, their associations with behavioral phenotypes of clinical interest, and the cross-syndrome overlap between the anxiety network and other affective syndromes in an adolescent sample.

Methods

We used the Boston Adolescent Neuroimaging of Depression and Anxiety (BANDA) dataset which comprises 203 clinical and healthy adolescents aged 14-17. Participants underwent a resting-state magnetic resonance imaging scan and completed the Child Behavior

SUBMITTER: Lim XYH 

PROVIDER: S-EPMC11846206 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature