Risk factors for developing irritable bowel syndrome: systematic umbrella review of reviews.

ABSTRACT:

Background

Irritable bowel syndrome (IBS) is a debilitating disorder affecting 4-9% of the global population. It is a multifaceted disorder with complex and varied causes. This review aims to consolidate the evidence regarding IBS risk factors by examining existing systematic reviews and meta-analyses, covering potential genetic, immunological, psychological, and dietary causes.

Methods

Systematic literature searches were conducted in MEDLINE, Embase and Cochrane library databases. Study selection and data extraction were conducted independently by four authors, with discrepancies resolved by consensus with a senior author. Systematic reviews examining risk factors of IBS development were eligible for review. Results were narratively synthesized. Quality of reviews were anal

SUBMITTER: Sulaimi F 

PROVIDER: S-EPMC11846330 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature