Quality of guidelines for infection management in sepsis: a critical appraisal using the AGREE II instrument.

ABSTRACT:

Objectives

The aim of this study was to systematically assess the methodological quality of current sepsis infection management guidelines and identify gaps in knowledge that limit evidence-based practice.

Methods

A systematic search was conducted to obtain guidelines for the management of sepsis infections (2012-2021), and three reviewers independently assessed the quality of eligible guidelines using Appraisal of Guidelines for Research and Evaluation (AGREE II) tool. The intraclass correlation coefficients (ICCs) were used to measure the agreement between reviewers. The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach was used to analyze the strength of recommendation and level of evidence of the guideline, and the number of recommendati

SUBMITTER: Yang GX 

PROVIDER: S-EPMC11846407 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature