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Is it time to abandon staging surgery and prolonged follow-up in patients with primary adult-type granulosa cell tumor?


ABSTRACT:

Background

As current literature does not provide sufficient data to support clear guidelines in patients with a rare adult-type granulosa cell tumor, we aim to investigate: (1) whether additional staging surgery following primary surgical treatment is necessary; (2) how long standard follow-up should be and (3) risk factors for disease recurrence.

Methods

A national multicenter prospective study was initiated in April 2018. Patients with suspected or confirmed adult-type granulosa cell tumor were eligible. Data on staging, follow-up and risk factors were both retrospectively and prospectively collected from medical records, and patients were followed until April 2024 or until death. Descriptive statistical analysis and survival analysis were performed using Cox regression m

SUBMITTER: Brink GJ 

PROVIDER: S-EPMC11846436 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature