Resting-state functional brain connectivity in female adolescents with first-onset anorexia nervosa.

ABSTRACT:

Objective

Women with anorexia nervosa (AN) have been shown to demonstrate differences in functional connectivity in brain regions associated with cognitive control, somatosensory processing, and emotion regulation. However, previous studies have been conducted on small samples and have inconsistent findings. Therefore, this study aimed to identify aberrant brain networks related to the core clinical symptoms of AN and to explore the longitudinal association with clinical outcome in a large population of adolescents experiencing their first episode of AN.

Methods

Functional MRI (fMRI) of brain resting-state functional connectivity (RS-FC) of female adolescents with first-onset AN (n = 56) were compared to age- and education-matched typically developing (TD) adolescents (n = 6

SUBMITTER: Bracke KFM 

PROVIDER: S-EPMC11846585 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature