Impact of positive surgical margin location after radical prostatectomy: a network meta-analysis.

ABSTRACT:

Objective

To perform a network meta-analysis comparing the impact of different positive surgical margin locations (Comparisons and intervention) on biochemical recurrence (Outcome) in patients undergoing radical prostatectomy (Population).

Methods

According to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines, a protocol was registered (PROSPERO: CRD42022119025) and a search across four databases was conducted (the MEDLINE, Scopus, Embase and Cochrane). The primary outcome was biochemical recurrence (BCR). A network meta-analysis was conducted. Further subgroup analysis was performed to evaluate studies exploring robot-assisted radical prostatectomy (RALP).

Results

Our search yielded 1249 unique results; 22 studies were analyse

SUBMITTER: John A 

PROVIDER: S-EPMC11846713 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature