Tanycytes from a bird's eye view: gene expression profiling of the tanycytic region under different seasonal states in the Svalbard ptarmigan.

ABSTRACT: In mammals and birds, tanycytes are known to regulate thyroid hormone conversion, and this process is central to the control of seasonal reproduction. In mammals, this cell type is also implicated in retinoic acid signalling, neurogenesis, and nutritional gatekeeping, all of which have been linked to hypothalamic regulation of energy metabolism. Less is known about these potential wider roles of tanycytes in birds. To address this gap, we combined LASER capture microdissection and transcriptomics to profile the tanycytic region in male Svalbard ptarmigan, a High Arctic species with photoperiod-dependent seasonal rhythms in reproductive activation and body mass. Short photoperiod (SP) adapted birds were transferred to constant light (LL) to trigger breeding and body mass loss. After five mo

SUBMITTER: Appenroth D 

PROVIDER: S-EPMC11846777 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature