Polyextremotolerant, opportunistic, and melanin-driven resilient black yeast Exophiala dermatitidis in environmental and clinical contexts.

ABSTRACT: Exophiala dermatitidis, a polyextremotolerant black yeast, thrives in diverse natural and human-made environments. Additionally, it is an opportunistic pathogen, capable of infecting immunocompromised individuals, particularly causing neurotropic infections. This study examined 41  E. dermatitidis strains from diverse environments, investigating their growth under different temperatures, NaCl concentrations, and pH levels. Optimal growth occurred at 28 °C, with large variations among strains at other temperatures, from 4 to 42 °C. Growth was enhanced at 5% NaCl, though strains also grew at 10% and 17% NaCl. Growth varied across different pH levels, from pH 2.5 to 12.5. Most strains showed the highest biofilm formation at 37 °C, α- and γ-hemolysis and resistance to antifungal agents. Better

SUBMITTER: de Leon LR 

PROVIDER: S-EPMC11846982 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature