Patterns of lymph node metastasis and treatment outcomes of parotid gland malignancies.

ABSTRACT:

Background

This study aimed to characterize the pattern of cervical lymph node spread and evaluate prognostic factors and outcomes of surgery and postoperative adjuvant therapy in primary parotid carcinoma (PPC).

Methods

We retrospectively enrolled 136 patients with PPC. The primary outcomes were disease-free survival (DFS) and overall survival (OS). We used Cox hazards models to assess variables influencing survival, and chi-square tests and logistic regression models to evaluate correlations between pN + and clinicopathological factors.

Results

Pathology-confirmed lymph node metastasis was detected in 60.0% and 84.1% of the patients with cT1-2 and cT3-4 tumors, respectively. The occult metastasis rate in cN0 was 55.2%. Level II metastasis was most common (93.2%), fo

SUBMITTER: Wang W 

PROVIDER: S-EPMC11847358 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature