Frailty repels the knife: The impact of frailty index on surgical intervention and outcomes.

ABSTRACT:

Objective

To assess the impact of frailty in patients with ovarian cancer on surgical procedures and outcomes.

Methods

A retrospective review of patients with stage II-IV ovarian cancer from April 2013 to September 2017 was performed. Patients were triaged by laparoscopy to determine primary resectability. The adjusted modified frailty index score (amFI) was calculated and amFI ≥2 classified as high frailty. Clinical outcomes, progression free survival (PFS) and overall survival (OS) were estimated.

Results

592 patients met inclusion criteria; amFI of 0, 1 and ≥ 2 was noted in 57%, 29%, and 14%, respectively. Patients with high frailty were less likely to be offered laparoscopic assessment for primary surgery (49% v. 43% v. 28% for amFI = 0, 1, and ≥ 2, p = 0.004), an

SUBMITTER: Handley KF 

PROVIDER: S-EPMC11847601 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature