Kidney Function and Incident Stroke and Dementia Using an Updated Estimated Glomerular Filtration Rate Equation Without Race: The Multi-Ethnic Study of Atherosclerosis.

ABSTRACT:

Rationale & objective

Equations for estimated glomerular filtration rate (eGFR) have previously included a coefficient for African American race. We evaluated and compared risk of incident stroke and dementia between old and new equations of eGFR for African American and non-African American participants.

Study design

Prospective observational study.

Setting & participants

Baseline values were collected from 6,814 participants in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort between 2000 and 2002. Participants were followed up until 2018. The analytic sample consisted of 6,646 participants (mean [SD] age 62 [10] years; 53% female; 39% White, 27% African American, 12% Chinese American, and 22% Hispanic/Latino).

Exposure

eGFR equation from 2021 based on

SUBMITTER: Moen SR 

PROVIDER: S-EPMC11847729 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature