Preoxygenation strategies before intubation in patients with acute hypoxic respiratory failure: a network meta-analysis.

ABSTRACT:

Background

Patients with acute hypoxic respiratory failure (AHRF) face life-threatening complications during tracheal intubation. Preoxygenation can enhance oxygen reserves and mitigate hypoxemia risk, but the optimal strategy remains unclear. This study aimed to identify the best preoxygenation strategy for these patients.

Methods

We conducted a network meta-analysis of studies published up to July 2024, evaluating conventional oxygen therapy (COT), high-flow nasal cannula (HFNC), non-invasive ventilation (NIV), and their combinations prior to intubation. Data were extracted and analyzed using pairwise and network meta-analysis within a Bayesian framework. Model selection was based on the deviance information criterion (DIC).

Results

A total of 11 randomized controll

SUBMITTER: Ye N 

PROVIDER: S-EPMC11847861 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature