Choroid plexus cysts on 7T MRI: Relationship to aging and neurodegenerative diseases.

ABSTRACT:

Introduction

The choroid plexus (CP) may play a crucial role in brain degeneration. We aim to assess whether CP cysts (CPCs), defined using ultra-high field magnetic resonance imaging (MRI), relate to aging and neurodegeneration.

Methods

We used multi-sequence 7T MRI to observe CPCs, characterizing their presence and characteristics in healthy younger controls, healthy older controls (OCs), patients with Alzheimer's disease (AD), patients with Parkinson's disease (PD), and patients with uremic encephalopathy. CP volume (CPV) and CPC characteristics were compared across groups, and associations between CPV and CPC features were analyzed across all subjects.

Results

The AD group showed a significantly higher presence and number of CPCs compared to other groups and also

SUBMITTER: Zhen Z 

PROVIDER: S-EPMC11848175 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature