Plasma expansion and renal perfusion in critical COVID-19 with AKI: A prospective case control study.

ABSTRACT:

Introduction

A decrease in renal perfusion during acute kidney injury (AKI) due to critical COVID-19 has previously been demonstrated. The objective of this study was to compare the effects of plasma expansion with a standardized fluid bolus on renal perfusion in critically ill patients with AKI compared to similar patients without AKI.

Methods

A case control study design was used to investigate group differences before and after a standardized intervention. ICU-treated COVID-19 patients without underlying kidney disease were assigned to two groups based on KDIGO Creatinine criteria for AKI. Renal perfusion was assessed by magnetic resonance imaging using phase contrast and arterial spin labeling before and directly after plasma expansion with 7.5 mL/kg Ringer's Acetate (Bax

SUBMITTER: Luther T 

PROVIDER: S-EPMC11848233 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature