Estimated pulse wave velocity associated with cognitive phenotypes in a rural older population in China: A cohort study.

ABSTRACT:

Introduction

To examine the longitudinal association between estimated pulse wave velocity (ePWV) and cognitive phenotypes in a rural Chinese older population.

Methods

This population-based study included 1857 dementia-free participants (age ≥60 years) who were examined in 2014 and followed in 2018. ePWV was calculated using age and mean blood pressure (MBP). Cognitive function was assessed using the Mini-Mental State Examination (MMSE) and neuropsychological tests. Dementia was diagnosed following the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) criteria. Data were analyzed using Cox proportional-hazards models, linear regression models, and restricted cubic spline (RCS) curves.

Results

Per 1-m/s increase in ePWV was associated with

SUBMITTER: Li J 

PROVIDER: S-EPMC11848348 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature