Psychotropic medication usage in sporadic versus genetic behavioral-variant frontotemporal dementia.

ABSTRACT:

Introduction

Psychotropic medication (PM) use in behavioral-variant frontotemporal dementia (bvFTD) is higher than in other dementias. However, no information exists on whether PM use differs between sporadic and genetic bvFTD.

Methods

We analyzed data from sporadic and genetic bvFTD participants with PM prescriptions in the Advancing Research and Treatment in Frontotemporal Lobar Degeneration/Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects study. We estimated ordinal odds ratio (OOR) of having more PM comparing sporadic and genetic bvFTD. Finally, we explored the neuropsychiatric symptom (NPS) combinations using classification and regression trees (CART).

Results

We included 263 with sporadic and 193 with genetic bvFTD. The OOR for sporadic bvFTD

SUBMITTER: Vargas-Gonzalez JC 

PROVIDER: S-EPMC11848424 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature