Bio-inspired Catalyst-Modified Photocathode for Bias-Free Photoelectrochemical NADH Regeneration.

ABSTRACT: Cofactors such as nicotinamide adenine dinucleotide (NADH) and its phosphorylated form (NADPH) play a crucial role in natural enzyme-catalyzed reactions for the synthesis of chemicals. However, the stoichiometric supply of NADH for artificial synthetic processes is uneconomical. Here, inspired by the process of cofactor NADPH regeneration in photosystem I (PSI), catalyst-modified photocathodes are constructed on the surface of polythiophene-based semiconductors (PTTH) via self-assembly for photoelectrochemical catalytic NADH regeneration. With the assistance of viologen (vi²⁺) electron transfer mediators (similar function as Ferredoxin in PSI) linked to the [Rh(Cp^*)(bpy)] catalyst, the Rh-vi²⁺@PTTH photocathode exhibits higher photocurrent density (-665 µA

SUBMITTER: Zhao Z 

PROVIDER: S-EPMC11848594 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature