Plain versus drug balloon and stenting in severe ischaemia of the leg (BASIL-3): open label, three arm, randomised, multicentre, phase 3 trial.

ABSTRACT:

Objective

To determine which primary endovascular revascularisation strategy represents the most clinically effective treatment for patients with chronic limb threatening ischaemia who require endovascular femoro-popliteal, with or without infra-popliteal, revascularisation.

Design

Three arm, open label, pragmatic, multicentre, randomised, phase 3 superiority trial (BASIL-3).

Setting

35 UK NHS vascular units.

Participants

Patients with chronic limb threatening ischaemia who required endovascular femoro-popliteal, with or without infra-popliteal, revascularisation.

Interventions

Participants were randomly assigned (1:1:1) to femoro-popliteal plain balloon angioplasty with or without bare metal stenting (PBA±BMS), drug coated balloon angioplasty with or wi

SUBMITTER: Bradbury AW 

PROVIDER: S-EPMC11848676 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature